Specifications
Immunogen
TIM-3:Ig fusion protein emulsified in complete Freund's adjuvant.
Conjugate
Functional Grade
Images
Flow Cytometry
CD8+ T cell expression of TIM3, LAG3, and 2B4 at distant tumors and spleens (n = 5/group).
Target
Alternative Names
HAVCR2; hepatitis A virus cellular receptor 2; hepatitis A virus cellular receptor 2 homolog; TIMD-3; HAVcr-2; T-cell membrane protein 3
Citations
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Hirai, A; Ohtsuka, N; et al. Role of Mouse Hepatitis Virus (MHV) Receptor Murine CEACAM1 in the Resistance of Mice to MHV Infection: Studies of Mice with Chimeric mCEACAM1a and mCEACAM1b. JOURNAL OF VIROLOGY 84:6654-6666(2010).
Nelson, DR; Soldevila-Pico, C; et al. Anti-interleukin-2 receptor therapy in combination with mycophenolate mofetil is associated with more severe hepatitis C recurrence after liver transplantation. LIVER TRANSPLANTATION 7:1064-1070(2001).