HIV type 1 Glycoprotein 41 [HRP] (DAG4281)

HIV type 1 Glycoprotein 41 [HRP], recombinant protein from E. coli Datasheet

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Product Overview
Recombinant HIV-1 gp41 Long, HRP-tagged
Specificity
Immunoreactive with all sera of HIV-I infected individuals.
Nature
Recombinant
Tag/Conjugate
HRP
Purity
Protein is > 95% pure as determined by 10% PAGE (coomassie staining) and RP-HPLC.
Concentration
1mg/ml, 50mM Tris-HCl, 10mM glutation, 60mM NaCl, 0.25% sarcosyl, 50% glycerol.
Storage
2-8°C short term, -20°C long term
Introduction
The human immunodeficiency virus (HIV) is a lentivirus (slowly replicating retrovirus) that causes the acquired immunodeficiency syndrome (AIDS), a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive. Without treatment, average survival time after infection with HIV is estimated to be 9 to 11 years, depending on the HIV subtype. Infection with HIV occurs by the transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk. Within these bodily fluids, HIV is present as both free virus particles and virus within infected immune cells.
Antigen Description
gp41/120 is the major HIV protein associated with the HIV envelope. It functions as the viral antireceptor or attachment protein. gp41 (or TM) traverses the envelope, whereas gp120 is present on the outer surface and is noncovalently attached to gp41. The
Keywords
env; Glycoprotein 41; gp41; TM; Transmembrane protein; HIV gp41 L

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