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The minimum detectable dose of Human EGFR/HER1 was determined to be approximately 46.88 pg/ml. This is defined as at least three times standard deviations above the mean optical density of 10replicates of the zero standard.
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Formica, V; Roselli, M; et al. Targeted therapy in first line treatment of RAS wild type colorectal cancer. WORLD JOURNAL OF GASTROENTEROLOGY 21:2871-2874(2015).
Paz-Ares, L; Mezger, J; et al. Necitumumab plus pemetrexed and cisplatin as first-line therapy in patients with stage IV non-squamous non-small-cell lung cancer (INSPIRE): an open-label, randomised, controlled phase 3 study. LANCET ONCOLOGY 16:328-337(2015).