Anti-EGFR monoclonal antibody (CABT-33610MH)

Mouse Anti-Human EGFR monoclonal antibody for FC, ICC/IF, IHC-Fr, IP Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2b
Clone
FHGS2
Species Reactivity
Mouse, Horse, Human
Immunogen
Human epidermoid carcinoma line A431; epitope mapped between aa 6-273 of human EGFR.
Conjugate
Unconjugated

Applications


Application Notes
ICC/IF: 1 μg/ml. Flow Cyt: 1μg/106 cells.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
EGFR; epidermal growth factor receptor; epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog) , ERBB; ERBB1; erythroblastic leukemia viral (v erb b) oncogene homolog (avian); EGFR
Entrez Gene ID
UniProt ID

Product Background


Pathway
Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Arf6 signaling events, organism-specific biosystem; Axon guidance, organism-specific biosystem; Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosy

Citations


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References


Formica, V; Roselli, M; et al. Targeted therapy in first line treatment of RAS wild type colorectal cancer. WORLD JOURNAL OF GASTROENTEROLOGY 21:2871-2874(2015).
Paz-Ares, L; Mezger, J; et al. Necitumumab plus pemetrexed and cisplatin as first-line therapy in patients with stage IV non-squamous non-small-cell lung cancer (INSPIRE): an open-label, randomised, controlled phase 3 study. LANCET ONCOLOGY 16:328-337(2015).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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