Optimal dilutions for each application to be determined by the researcher. Prepare working dilution immediately before use.
General Notes
This antibody can be used for evaluation of Duocarmycin-based antibody-drug conjugates (ADCs). Duocarmycin is a class of potent antitumor compounds derived from the bacterium Streptomyces species. Duocarmycin works by intercalating into the DNA minor groove and causing DNA strand cleavage, ultimately inducing cell cycle arrest and apoptosis in cancer cells. Due to its specificity and high potency, duocarmycin is being explored for use in ADCs as a targeted cancer therapy.
Target
Alternative Names
duocarmycins;
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
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