ELISA; Matched pair Antibody available for DM1[BSA], DM1 Antibody(Cat.# CABT-L3105)
Format
Liquid
Concentration
Batch dependent - please inquire should you have specific requirements.
Buffer
0.01M PBS, pH 7.2
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Antigen Description
Mertansine, also called DM1 is a thiol-containing maytansinoid that for therapeutic purposes isattached to a through reaction of the thiol group with a linker structure to create an ibody-drug conjugate (ADC). Mertansine is a tubulin inhibitor, meaning that it inhibits the assembly of microtubules by binding to tubulin (at the rhizoxin binding site). Ravtansine/soravtansine (DM4), chemical derivative of maytansine, used as a cytotoxic component of ibody-drug conjugates.
Keywords
Mertansine
Maytansinoid DM 1; UNII-DDZ29HGH0E; DDZ29HGH0E
Citations
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COA
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