Introduction
Dihydrocodeinone (DHC) is a natural alkaloid found in opium poppies (Papaver somniferum). It is a potent opioid agonist that binds to opioid receptors in the brain and central nervous system. DHC has a slower onset and longer duration of action compared to other opioids, and it may be used as a substitution treatment for opioid addiction. It is also used in the pharmaceutical industry for the synthesis of other opioid derivatives. However, due to its potency and addiction potential, DHC is a controlled substance in many countries and its recreational use is generally discouraged.
Keywords
Dihydrocodeinone; DHC
Citations
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Hutchinson, MR; Menelaou, A; et al. CYP2D6 and CYP3A4 involvement in the primary oxidative metabolism of hydrocodone by human liver microsomes. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY 57:287-297(2004).
BIAGINI, RE; BERNSTEIN, DM; et al. EVALUATION OF CUTANEOUS RESPONSES AND LUNG-FUNCTION FROM EXPOSURE TO OPIATE COMPOUNDS AMONG ETHICAL NARCOTICS-MANUFACTURING WORKERS. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 89:108-118(1992).
COA
Certificate of Analysis
