This paratope specific, inhibitory anti-idiotypic antibody binds specifically to brentuximab and brentuximab vedotin.
Suitable for anti-drug antibody (ADA) assay as a surrogate positive control or reference standard.
Summary
Specifications
Antibody Isotype
IgG1, κ
Clone
AbD39659ia
Immunogen
Brentuximab vedotin
Conjugate
Unconjugated
Applications
Application Notes
Suitable for use in ADA bridging ELISA. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
General Notes
This antibody binds specifically to brentuximab and brentuximab vedotin.It can be used as a calibrator in ADA assays. Brentuximab vedotin (Adcetris) is an antibody-drug conjugate comprising an anti-CD30 monoclonal antibody linked to a potent cytotoxic agent, monomethyl auristatin E (MMAE). It is approved for treating Hodgkin lymphoma and anaplastic large cell lymphoma.
Target
Alternative Names
Brentuximab vedotin; Adcetris
Citations
Publication ()
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