Molecular Weight
app. 44 kDa
Alternative Names
azithromycin; Zithromax; Sumamed; Zitromax; Azithromycine
Purity
chromatography, dialysis
Concentration
1 mg/mL working concentration
Reconstitution
Reconstitute with 1 ml PBS without azide.
Introduction
Azithromycin is an azalide, derived from erythromycin, and a member of a subclass of macrolide antibiotics with bacteriocidal and bacteriostatic activities. Azithromycin reversibly binds to the 50S ribosomal subunit of the 70S ribosome of sensitive microorganisms, thereby inhibiting the translocation step of protein synthesis, wherein a newly synthesized peptidyl tRNA molecule moves from the acceptor site on the ribosome to the peptidyl (donor) site, and consequently inhibiting RNA-dependent protein synthesis leading to cell growth inhibition and cell death.
Antigen Description
Azithromycin, covalently linked to horseradish peroxidase
Keywords
drug-HRP conjugate, drug-conjugate, Azithromycin HRP conjugate
Citations
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