High affinity to the HAstV-1 spike, neutralizes HAstV1 in Caco-2 cells
Suitable for Neut, ELISA
Isotype: IgG
Clonality: Monoclonal
Various conjugated forms available upon request.
Summary
Specifications
Antibody Isotype
IgG1
Clone
3H4
Species Reactivity
Astrovirus
Immunogen
The original antibody was obtained by immunizing mice with recombinant spike protein
Conjugate
Unconjugated
Applications
Application Notes
Neut, ELISA Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
General Notes
Human astroviruses (HAstVs) are common etiological agents of acute gastroenteritis in children, the elderly, and immunocompromised patients. It has been reported that Antibody 3B4 targets the upper variable loop regions of the HAstV spike protein, and antibody 3H4 targets a novel region near the base of the spike that is more conserved. These antibodies can neutralize HAstV1 in Caco-2 cells.
Target
Alternative Names
Astrovirus; HAstV
Citations
Publication ()
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