Anti-XIAP Polyclonal Antibody (CABT-L2221) Knockout Validated

Rabbit Anti-Human XIAP (Met1~Ser497) Polyclonal Antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human, Pig
Immunogen
Recombinant fragment corresponding to human XIAP (Met1~Ser497)
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution: WB: 0.5-2 ug/ml
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Knockout Varification: Lane 1: Wild-type 293T cell lysate. Lane 2: XIAP knockout 293T cell lysate. Predicted MW: 56kd, Observed MW: 55kd
Figure. Western Blot. Sample. Lane1: Human HepG2 Cells; Lane2: Human 293T Cells; Lane3: Porcine Heart Tissue; Lane4: Porcine Liver Tissue.

Target


Alternative Names
BIRC4; API3; ILP1; MIHA; XLP2; Baculoviral IAP Repeat-Containing 4
Entrez Gene ID
UniProt ID

Product Background


Pathway
Apoptosis; Apoptotic factor-mediated response; BMP receptor signaling; Caspase cascade in apoptosis; Disease; Focal adhesion; HTLV-I infection; Intrinsic Pathway for Apoptosis;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Kato, K; Tanaka, T; et al. Protein kinase C stabilizes X-linked inhibitor of apoptosis protein (XIAP) through phosphorylation at Ser(87) to suppress apoptotic cell death. PSYCHOGERIATRICS 11:90-97(2011).
Tikoo, A; O'Reilly, L; et al. Tissue distribution of Diablo/Smac revealed by monoclonal antibodies. CELL DEATH AND DIFFERENTIATION 9:710-716(2002).

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