Anti-FAK Polyclonal Antibody (CABT-L2131) Knockout Validated

Rabbit Anti-Human FAK (Gly798~Ala1041) Polyclonal Antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Recombinant fragment corresponding to human PTK2 (Gly798~Ala1041)
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution: WB: 0.5-2 ug/ml
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Knockout Varification: Lane 1: Wild-type Jurkat cell lysate. Lane 2: FAK knockout Jurkat cell lysate. Predicted MW: 39, 48, 63, 100, 120kd, Observed MW: 120kd
Western Blot. Sample. Human Jurkat cell lysate.
Western Blot. Sample. Human K562 cell lysate.
Western Blot. Sample. Human Lung lysate.

Target


Alternative Names
PTK2; FADK; FAK1; Pp125FAK; PPP1R71; Protein Tyrosine Kinase 2
UniProt ID

Product Background


Pathway
Alpha6-Beta4 Integrin Signaling Pathway; Amoebiasis; Androgen receptor signaling pathway; Angiogenesis; Apoptosis; Apoptotic cleavage of cellular proteins; Apoptotic execution phase; Axon guidance;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Mayboroda, O; Schluter, K; et al. Differential colocalization of profilin with microfilaments in PtK2 cells. CELL MOTILITY AND THE CYTOSKELETON 37:166-177(1997).
Saredi, A; Howard, L; et al. Phosphorylation regulates the assembly of NuMA in a mammalian mitotic extract. JOURNAL OF CELL SCIENCE 110:1287-1297(1997).

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