AMER1 mutants destabilize the destruction complex; APC truncation mutants are not K63 polyubiquitinated; APC truncation mutants have impaired AXIN binding; APC/C-mediated degradation of cell cycle proteins; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdc20 mediated degradation of mitotic proteins; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell c
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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Tan, YL; Peng, X; et al. Effects of tumor necrosis factor-alpha on the 26S proteasome and 19S regulator in skeletal muscle of severely scalded mice. JOURNAL OF BURN CARE & RESEARCH 27:226-233(2006).
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