AMER1 mutants destabilize the destruction complex; APC truncation mutants are not K63 polyubiquitinated; APC truncation mutants have impaired AXIN binding; APC/C-mediated degradation of cell cycle proteins; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdc20 mediated degradation of mitotic proteins; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell c
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