Anti-MPI Polyclonal Antibody (CABT-L2232) Knockout Validated

Rabbit Anti-Human MPI (Ala2~Leu423) Polyclonal Antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human, Pig
Immunogen
Recombinant fragment corresponding to human MPI (Ala2~Leu423)
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution: WB: 0.2-2 ug/ml; 1:250-2500
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Knockout Varification: Lane 1: Wild-type 293T cell lysate. Lane 2: MPI knockout 293T cell lysate. Predicted MW: 47, 40kd, Observed MW: 40kd
Western Blot. Sample. Human 293T cell lysate.
Western Blot. Sample. Human Lung lysate.
Western Blot. Sample. Porcine Cerebrum lysate.

Target


Alternative Names
PMI1; Mannose-6-Phosphate Isomerase; Phosphohexomutase; Phosphomannose isomerase
Entrez Gene ID
UniProt ID

Product Background


Pathway
Amino sugar and nucleotide sugar metabolism; Asparagine N-linked glycosylation; Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein; D-mannose degradation; Defective ALG1 causes ALG1-CDG (CDG-1k); Defective ALG11 causes ALG11-CDG (CDG-1p); Defective ALG12 causes ALG12-CDG (CDG-1g); Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS);

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Geissler, K; et al. Therapeutic potential of thrombopoietin. WIENER KLINISCHE WOCHENSCHRIFT 112:829-834(2000).
Baharfard, N; Shiroodi, MK; et al. Myocardial perfusion imaging using a technetium-99m Sestamibi in asymptomatic and low risk for coronary artery disease patients with diagnosed systemic lupus erythematosus. PERFUSION-UK 26:151-157(2011).

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