Anti-MGMT Polyclonal Antibody (CABT-L2182) Knockout Validated

Rabbit Anti-Human MGMT (Met1~Asn207) Polyclonal Antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Recombinant fragment corresponding to human MGMT (Met1~Asn207)
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution: WB: 0.5-2 ug/ml
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Knockout Varification: Lane 1: Wild-type Jurkat cell lysate. Lane 2: MGMT knockout Jurkat cell lysate. Predicted MW: 21kd, Observed MW: 22kd
Figure. Western Blot. Sample. Human Jurkat Cells.

Target


Alternative Names
Methylated-DNA--Protein-Cysteine Methyltransferase; 6-O-methylguanine-DNA methyltransferase; Methylated-DNA--protein-cysteine methyltransferase
Entrez Gene ID
UniProt ID

Product Background


Pathway
DNA Damage Reversal; DNA Repair;

Citations


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References


Haberler, C; Wohrer, A; et al. Clinical Neuropathology practice news 2-2014: ATRX, a new candidate biomarker in gliomas. CLINICAL NEUROPATHOLOGY 33:108-111(2014).
Pietrantonio, F; Maggi, C; et al. FOLFOX-4 Chemotherapy for Patients With Unresectable or Relapsed Peritoneal Pseudomyxoma. ONCOLOGIST 19:845-850(2014).

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