Anti-MCM2 Polyclonal Antibody (CABT-L2150) Knockout Validated

Rabbit Anti-Human MCM2 (Ile473~Val679) Polyclonal Antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Recombinant fragment corresponding to human MCM2 (Ile473~Val679)
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution: WB: 0.5-2 ug/ml
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Knockout Varification: Lane 1: Wild-type K562 cell lysate. Lane 2: MCM2 knockout K562 cell lysate. Predicted MW: 101kd, Observed MW: 120kd
Figure. Western Blot. Sample. Lane1: Human K562 Cells; Lane2: Human Hela Cells; Lane3: Human Jurkat Cells.

Target


Alternative Names
BM28; CCNL1; CDCL1; Cdc19; Mitotin; DNA Replication Licensing Factor MCM2
Entrez Gene ID
UniProt ID

Product Background


Pathway
Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Assembly of the pre-replicative complex; Cell Cycle; Cell Cycle Checkpoints; Cell Cycle, Mitotic; Cell cycle; DNA Replication;

Citations


Have you cited CABT-L2150 in a publication? Let us know and earn a reward for your research.

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

Customer Reviews


Write a review, share your experiences with others and get rewarded !
Product Name Cat. No. Applications Host Species Datasheet Price Add to Basket

References


Okishio, N; Adachi, Y; et al. Fission yeast Nda1 and Nda4, MCM homologs required for DNA replication, are constitutive nuclear proteins. JOURNAL OF CELL SCIENCE 109:319-326(1996).
Carlage, T; Kshirsagar, R; et al. Analysis of dynamic changes in the proteome of a Bcl-XL overexpressing Chinese hamster ovary cell culture during exponential and stationary phases. BIOTECHNOLOGY PROGRESS 28:814-823(2012).

Online Inquiry

Name:
Phone: *
E-mail Address: *
Service & Products Interested: *
Project Description:
Verification Code: * Please input "diagnostics" as verification code.

Online Inquiry

  Interested in larger quantities ? request a quote!
  Protocol may be improved. Please feel free to contact us to obtain the latest version.!

Ordering Information

Payment methods we support:
Invoice / Purchase Order
Credit card

OUR PROMISE TO YOU Guaranteed product quality expert customer support

Inquiry Basket