Anti-KRT1 Polyclonal Antibody (CABT-L2045) Knockout Validated

Rabbit Anti-Human KRT1 (Glu487~Arg644) Polyclonal Antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human, Mouse, Rat, Pig
Immunogen
Recombinant fragment corresponding to human KRT1 (Glu487~Arg644)
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution: WB: 0.5-2 ug/ml; 1:350-1400
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Knockout Varification: Lane 1: Wild-type A431 cell lysate. Lane 2: KRT1 knockout A431 cell lysate. Predicted MW: 66kDa, Observed MW: 66kDa
Figure. Western Blot. Sample. Lane1: Human A375 Cells; Lane2: Human H460 Cells; Lane3: Human Hela Cells; Lane4: Mouse Pancreas Tissue.

Target


Alternative Names
CK1; EHK1; K1; KRT1A; KRT1-A; Cytokeratin 1
Entrez Gene ID
UniProt ID

Product Background


Pathway
Corticotropin-releasing hormone; Regulation of Wnt-mediated beta catenin signaling and target gene transcription;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Tamai, Y; Ishikawa, T; et al. Cytokeratins 8 and 19 in the mouse placental development. JOURNAL OF CELL BIOLOGY 151:563-572(2000).
Virtanen, M; Gedde-Dahl, T; et al. Phenotypic/genotypic correlations in patients with epidermolytic hyperkeratosis and the effects of retinoid therapy on keratin expression. ACTA DERMATO-VENEREOLOGICA 81:163-170(2001).

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