Anti-FOLR1 Polyclonal Antibody (CABT-L2015) Knockout Validated

Rabbit Anti-Human FOLR1 (Arg25~Ser234) Polyclonal Antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Recombinant fragment corresponding to human FOLR1 (Arg25~Ser234)
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution: WB: 0.5-2 ug/ml
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Knockout Varification: Lane 1: Wild-type Hela cell lysate. Lane 2: FOLR1 knockout Hela cell lysate. Predicted MW: 30kDa, Observed MW: 35kDa
Figure. Western Blot. Sample. Lane1: Human Hela Cells ; Lane2: Human Mcf7 Cells.

Target


Alternative Names
FBP; FOLR; FR-alpha; MOv18; Adult folate-binding protein; KB cells FBP
Entrez Gene ID
UniProt ID

Product Background


Pathway
Endocytosis;

Citations


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References


Nunez, MI; Behrens, C; et al. High Expression of Folate Receptor Alpha in Lung Cancer Correlates with Adenocarcinoma Histology and Mutation. JOURNAL OF THORACIC ONCOLOGY 7:833-840(2012).
Lin, JM; Spidel, JL; et al. The antitumor activity of the human FOLR1-specific monoclonal antibody, farletuzumab, in an ovarian cancer mouse model is mediated by antibody-dependent cellular cytotoxicity. CANCER BIOLOGY & THERAPY 14:1032-1038(2013).

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