Anti-Bid Polyclonal Antibody (CABT-L2104) Knockout Validated

Rabbit Anti-Human Bid (Met1~Asp195) Polyclonal Antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Recombinant fragment corresponding to human BID (Met1~Asp195)
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution: WB: 0.5-2 ug/ml
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Knockout Varification: Lane 1: Wild-type Jurkat cell lysate. Lane 2: Bid knockout Jurkat cell lysate. Predicted MW: 22kd, Observed MW: 22kd
Figure. Western Blot. Sample. Human Lung Tissue.

Target


Alternative Names
p22 BID
Entrez Gene ID
UniProt ID

Product Background


Pathway
Activation and oligomerization of BAK protein; Activation of BAD and translocation to mitochondria; Activation of BH3-only proteins; Activation, myristolyation of BID and translocation to mitochondria; Activation, translocation and oligomerization of BAX; Alzheimers disease; Alzheimers Disease; Amyotrophic lateral sclerosis (ALS);

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Uriarte, SM; Joshi-Barve, S; et al. Akt inhibition upregulates FasL, downregulates c-FLIPs and induces caspase-8-dependent cell death in Jurkat T lymphocytes. CELL DEATH AND DIFFERENTIATION 12:233-242(2005).
Sung, ES; Park, KJ; et al. The proteasome inhibitor MG132 potentiates TRAIL receptor agonist-induced apoptosis by stabilizing tBid and Bik in human head and neck squamous cell carcinoma cells. EXPERIMENTAL CELL RESEARCH 318:1564-1576(2012).

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