Anti-ACTN2 Polyclonal Antibody (CABT-L2036) Knockout Validated

Rabbit Anti-Human ACTN2 (Met1~His254) Polyclonal Antibody for WB Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human, Mouse
Immunogen
Recombinant fragment corresponding to human ACTN2 (Met1~His254)
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution: WB: 0.5-2 ug/ml
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Knockout Varification: Lane 1: Wild-type Hela cell lysate. Lane 2: ACTN2 knockout Hela cell lysate. Predicted MW: 104kDa, Observed MW: 104kDa
Western Blot. Sample. Human Hela cell lysate.
Western Blot. Sample. Mouse Lung lysate.
Western Blot. Sample. Mouse Skeletal muscle lysate.

Target


Alternative Names
Alpha-actinin skeletal muscle isoform 2; F-actin cross-linking protein
Entrez Gene ID
UniProt ID

Product Background


Pathway
Activation of NMDA receptor upon glutamate binding and postsynaptic events; Adherens junction; Amoebiasis; Arrhythmogenic right ventricular cardiomyopathy; Arrhythmogenic right ventricular cardiomyopathy (ARVC); CREB phosphorylation through the activation of CaMKII; CREB phosphorylation through the activation of Ras; Cell-Cell communication;

Citations


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References


Linnemann, A; van der Ven, PFM; et al. The sarcomeric Z-disc component myopodin is a multiadapter protein that interacts with filamin and alpha-actinin. EUROPEAN JOURNAL OF CELL BIOLOGY 89:681-692(2010).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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Order Info: Anti-ACTN2 Polyclonal Antibody

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