The protein encoded by this gene transports zinc from the Golgi and endoplasmic reticulum to the cytoplasm. This transport may be important for activation of tyrosine kinases, some of which could be involved in cancer progression. Therefore, modulation of the encoded protein could be useful as a therapeutic agent against cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Function
metal ion transmembrane transporter activity; protein binding
Synonyms
SLC39A7; solute carrier family 39 (zinc transporter), member 7; KE4; HKE4; ZIP7; RING5; H2-KE4; D6S115E; D6S2244E; zinc transporter SLC39A7; zrt-, Irt-like protein 7; Ke4 gene, mouse, human homolog of; solute carrier family 39 member 7; histidine-rich membrane protein Ke4; really interesting new gene 5 protein; HLA class II region expressed gene KE4
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