Human SLC39A7 blocking peptide (CDBP3244)

Synthetic Human SLC39A7 blocking peptide for BL

Product Overview
Blocking peptide for anti-ZIP7 antibody
Target
ZIP7
Nature
Synthetic
Species Reactivity
Human
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not suitable for human or animal consumption.
Procedure
None
Format
Liquid
Concentration
200 μg/ml
Size
50 μg
Buffer
PBS containing 0.02% sodium azide
Preservative
0.02% Sodium Azide
Storage
Store at -20℃, stable for one year.
UniProt ID
Antigen Description
The protein encoded by this gene transports zinc from the Golgi and endoplasmic reticulum to the cytoplasm. This transport may be important for activation of tyrosine kinases, some of which could be involved in cancer progression. Therefore, modulation of the encoded protein could be useful as a therapeutic agent against cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Function
metal ion transmembrane transporter activity;
Synonyms
SLC39A7; solute carrier family 39 (zinc transporter), member 7; HKE4, HLA class II region expressed gene KE4; zinc transporter SLC39A7; D6S2244E; H2 KE4; KE4; RING5; ZIP7; Ke4 gene, mouse, human homolog of; solute carrier family 39 member 7; histidine-rich membrane protein Ke4; really interesting new gene 5 protein; HLA class II region expressed gene KE4; HKE4; H2-KE4; D6S115E;

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References


Hogstrand, C; Kille, P; et al. Zinc transporters and cancer: a potential role for ZIP7 as a hub for tyrosine kinase activation. TRENDS IN MOLECULAR MEDICINE 15:101-111(2009).
He, L; Girijashanker, K; et al. ZIP8, member of the solute-carrier-39 (SLC39) metal-transporter family: Characterization of transporter properties. MOLECULAR PHARMACOLOGY 70:171-180(2006).

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