Belongs to the krueppel C2H2-type zinc-finger protein family.Contains 20 C2H2-type zinc fingers.Contains 1 KRAB domain.
Alternative Names
The C2H2-type zinc finger 2 to 6 are necessary and sufficient for discrete Cajal bodies localization. The C2H2-type zinc finger 5 to 10 are necessary and sufficient for interaction with LSM11. The C2H2-type zinc finger 2 to 8 are necessary for interaction
Format
Liquid
Preservative
None
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.
Involved in histone 3'-end pre-mRNA processing by associating with U7 snRNP and interacting with SLBP/pre-mRNA complex. Increases histone 3'-end pre-mRNA processing but has no effect on U7 snRNP levels, when overexpressed. Required for cell cycle progression from G1 to S phases.
Function
DNA binding; metal ion binding; protein binding;
Synonyms
ZNF473; zinc finger protein 473; ZN473; HZFP100; zfp-100; zinc finger protein ZFP100; zinc finger protein 100 homolog;
Citations
Publication ()
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