Involved in histone 3-end pre-mRNA processing by associating with U7 snRNP and interacting with SLBP/pre-mRNA complex. Increases histone 3-end pre-mRNA processing but has no effect on U7 snRNP levels, when overexpressed. Required for cell cycle progression from G1 to S phases.
Pathway
Cleavage of Growing Transcript in the Termination Region; Generic Transcription Pathway; RNA Polymerase II Transcription; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
Citations
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