This gene encodes a Z-DNA binding protein. The encoded protein plays a role in the innate immune response by binding to foreign DNA and inducing type-I interferon production. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Function
DNA binding; RNA binding; double-stranded RNA adenosine deaminase activity; left-handed Z-DNA binding; protein binding
Synonyms
ZBP1; Z-DNA binding protein 1; DAI; DLM1; DLM-1; C20orf183; Z-DNA-binding protein 1; DNA-dependent activator of IRFs; DNA-dependent activator of IFN-regulatory factors; tumor stroma and activated macrophage protein DLM-1; DNA-dependent activator of interferon regulatory factors
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