Anti-ZBP1 monoclonal antibody (DCABH-761)

Mouse anti-Human ZBP1 monoclonal antibody for WB, IHC-P Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Species Reactivity
Human
Immunogen
Recombinant fragment: AQAPADPGRE GHLEQRILQV LTEAGSPVKL AQLVKECQAP KRELNQVLYR MKKELKVSLT SPATWCLGGT DPEGEGPAEL ALSSPAKRPQ QHAATIPET, corresponding to N terminal amino acids 2-100 of Human Z DNA binding protein (NP_110403) with a proprietary tag.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1 - 5 μg/ml; IHC-P: 3 μg/ml;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
ZBP1; Z-DNA binding protein 1; C20orf183, chromosome 20 open reading frame 183; Z-DNA-binding protein 1; DAI; dJ718J7.3
Entrez Gene ID
UniProt ID

Product Background


Pathway
Cytosolic DNA-sensing pathway, organism-specific biosystem; Cytosolic DNA-sensing pathway, conserved biosystem; Cytosolic sensors of pathogen-associated DNA, organism-specific biosystem; DAI mediated induction of type I IFNs, organism-specific biosystem; IRF3 mediated activation of type 1 IFN, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem;

Citations


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References


Zhang, JY; Chan, EKL; et al. A novel cytoplasmic protein with RNA-binding motifs is an autoantigen in human hepatocellular carcinoma. JOURNAL OF EXPERIMENTAL MEDICINE 189:1101-1110(1999).
Stevenson, FK; Ottensmeier, CH; et al. DNA vaccines against cancer come of age. CURRENT OPINION IN IMMUNOLOGY 22:264-270(2010).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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