Product Overview
Blocking/Immunizing peptide for anti-VPS29 (C Terminus) antibody
Target
VPS29 (C Terminus)
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
This gene belongs to a group of vacuolar protein sorting (VPS) genes that, when functionally impaired, disrupt the efficient delivery of vacuolar hydrolases. The protein encoded by this gene is a component of a large multimeric complex, termed the retromer complex, which is involved in retrograde transport of proteins from endosomes to the trans-Golgi network. This VPS protein may be involved in the formation of the inner shell of the retromer coat for retrograde vesicles leaving the prevacuolar compartment. Alternative splice variants encoding different isoforms and representing non-protein coding transcripts have been found for this gene. [provided by RefSeq, Aug 2013]
Function
hydrolase activity, acting on ester bonds; metal ion binding; phosphoserine phosphatase activity;
Synonyms
VPS29; vacuolar protein sorting 29 homolog (S. cerevisiae); vacuolar protein sorting 29 (yeast homolog) , vacuolar protein sorting 29 (yeast); vacuolar protein sorting-associated protein 29; DC7; DC15; PEP11; hVPS29; PEP11 homolog; x 007 protein; retromer protein; vesicle protein sorting 29; vacuolar sorting protein VPS29/PEP11; FLJ20492; DKFZp564F0223;
Citations
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Oliviusson, P; Heinzerling, O; et al. Plant retromer, localized to the prevacuolar compartment and microvesicles in Arabidopsis, may interact with vacuolar sorting receptors. PLANT CELL 18:1239-1252(2006).
Kim, E; Lee, JW; et al. Identification of novel retromer complexes in the mouse testis. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 375:16-21(2008).