A synthetic peptide from the c-terminal of mouse Vacuolar protein sorting-associated protein 29 (Vesicle protein sorting 29, VPS29) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in rat, human, chicken, z.
Conjugate
Unconjugated
Target
Alternative Names
VPS29; vacuolar protein sorting 29 homolog (S. cerevisiae); vacuolar protein sorting 29 (yeast homolog) , vacuolar protein sorting 29 (yeast); vacuolar protein sorting-associated protein 29; DC7; DC15; PEP11; hVPS29; PEP11 homolog; x 007 protein; retromer protein; vesicle protein sorting 29; vacuolar sorting protein VPS29/PEP11; FLJ20492; DKFZp564F0223;
Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA).
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Citations
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Oliviusson, P; Heinzerling, O; et al. Plant retromer, localized to the prevacuolar compartment and microvesicles in Arabidopsis, may interact with vacuolar sorting receptors. PLANT CELL 18:1239-1252(2006).
Kim, E; Lee, JW; et al. Identification of novel retromer complexes in the mouse testis. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 375:16-21(2008).
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COA
Certificate of Analysis
