Tag/Conjugate
Unconjugated
Antigen Description
This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral immunity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Function
CARD domain binding; protein binding; protein kinase binding; signal transducer activity
Synonyms
MAVS; mitochondrial antiviral signaling protein; IPS1; VISA; IPS-1; CARDIF; mitochondrial antiviral-signaling protein; IFN-B promoter stimulator 1; CARD adaptor inducing IFN-beta; virus-induced signaling adaptor; virus-induced-signaling adapter; CARD adapter inducing interferon beta; putative NF-kappa-B-activating protein 031N; interferon beta promoter stimulator protein 1
Citations
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Song, T; Wei, CW; et al. c-Abl tyrosine kinase interacts with MAVS and regulates innate immune response. FEBS LETTERS 584:33-38(2010).
Nistal-Villan, E; Gack, MU; et al. Negative Role of RIG-I Serine 8 Phosphorylation in the Regulation of Interferon-beta Production. JOURNAL OF BIOLOGICAL CHEMISTRY 285:20252-20261(2010).
COA
Certificate of Analysis
