Anti-MAVS (aa 100-200) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Mouse; Human

Immunogen

Synthetic peptide derived from within residues 100 - 200 of Human MAVS. ( Immunogen available as DAG-P0613 )

Conjugate

Application Notes

IHC-P: 1μg/ml; ICC/IF: 1μg/ml; WB: 1μg/ml;

Alternative Names

MAVS; mitochondrial antiviral signaling protein; IPS1; VISA; IPS-1; CARDIF; mitochondrial antiviral-signaling protein; IFN-B promoter stimulator 1; CARD adaptor inducing IFN-beta; virus-induced signaling adaptor

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral immunity. Multiple transcript variants encoding different isoforms have been found for this gene.

Pathway

Cytosolic DNA-sensing pathway, organism-specific biosystem; Cytosolic DNA-sensing pathway, conserved biosystem; Hepatitis C, organism-specific biosystem; Hepatitis C, conserved biosystem; Herpes simplex infection, organism-specific biosystem; Herpes simplex infection, conserved biosystem; Immune System, organism-specific biosystem; Influenza A, organism-specific biosystem; Influenza A, conserved biosystem; Innate Immune System, organism-specific biosystem; Measles, organism-specific biosystem; M