Human VAV3 blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-VAV3 antibody

Target

VAV3

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Gene ID

10451

UniProt ID

Q9UKW4

Antigen Description

This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Function

GTPase activator activity; Rac guanyl-nucleotide exchange factor activity; SH3/SH2 adaptor activity; epidermal growth factor receptor binding; guanyl-nucleotide exchange factor activity; metal ion binding; protein binding;

Synonyms

VAV3; vav 3 guanine nucleotide exchange factor; vav 3 oncogene; guanine nucleotide exchange factor VAV3; VAV-3; FLJ40431;