This gene encodes a protein that is involved in innate and adaptive immune response by regulating toll-like receptor signaling. The encoded protein traffics nucleotide sensing toll-like receptors to the endolysosome from the endoplasmic reticulum. Deficiency of the encoded protein has been associated with herpes simplex encephalitis. [provided by RefSeq, Feb 2014]
Synonyms
UNC93B1; unc-93 homolog B1 (C. elegans); IIAE1; UNC93; UNC93B; Unc-93B1; protein unc-93 homolog B1; unc93 homolog B1; unc-93 related protein
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