Human UNC13B blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-UNC13B antibody

Target

UNC13B

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis. [provided by RefSeq, Jul 2008]

Function

metal ion binding; receptor activity; signal transducer activity;

Synonyms

UNC13B; unc-13 homolog B (C. elegans); unc 13 like (C. elegans) , UNC13; protein unc-13 homolog B; hmunc13; Unc13h2; munc13-2; homolog of rat Munc13 (diacylglycerol-binding); UNC13; MUNC13; MGC133279; MGC133280;