Specificity
Expressed in fetal tail bud, posterior spinal tissue, intervertebral disk and testis. Also expressed in adult testis, kidney, lung, muscle and thymus.
Tag/Conjugate
Unconjugated
SequenceSimilarities
Contains 1 T-box DNA-binding domain.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.
Antigen Description
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Knockout studies in mice indicate that this gene is important for specification of paraxial mesoderm structures. [provided by RefSeq, Aug 2008]
Function
DNA binding; RNA polymerase II activating transcription factor binding; RNA polymerase II transcription factor binding; RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; sequence
Synonyms
TBX6; T-box 6; SCDO5; T-box transcription factor TBX6; T-box protein 6;
Citations
Publication ()
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COA
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