Rabbit Anti-Human TTC19 (a.a. 41-383) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse; Rat

Immunogen

Recombinant human TTC19 protein; Source: E. coli derived, PKG; Tag: GST; Domain: 41-383 aa of BC011698

Conjugate

Application Notes

WB: 1:500-1:1000
IHC: 1:50-1:500

General Notes

This product (Catalog No. CABT-BL5914) is a rabbit-derived polyclonal antibody raised against human TTC19, targeting the amino acid region 41–383 of the protein. This antibody exhibits cross-reactivity with Human TTC19 from mouse and rat. It has been affinity purified by Protein A. TTC19 is a subunit of mitochondrial respiratory chain complex III and is proposed to preserve the structural and functional integrity of complex III. Loss-of-function mutations in TTC19 have been found in patients with complex III deficiency associated with heterogeneous neurological syndromes. The precursor TTC19 was detected as a 43 kDa cytoplasmic protein, while the mature TTC19 with the mitochondrial targeting sequence cleaved was observed as 35 kDa by SDS-PAGE. (PMID: 21278747).
CABT-BL5914 is suitable for use in Western blot (WB) (1:500–1:1,000), IHC (1:50–1:500) applications.
CABT-BL5914 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

2010204O13Rik; TPR repeat protein 19; TTC19

Entrez Gene ID

UniProt ID