Investigation of Resveratrol Adsorption on Pine Pollen Grains: A First-Principles Study
CHEMISTRYSELECT
Authors: Zhao, Meilian; Chen, Rong; Bai, Jing; Guo, Jinlin; Qin, Wenli; Tong, Xinxin; Yan, Jie
Abstract
Pollen grains have been successfully used as a solid-phase extraction sorbent to separate trans-resveratrol (TRA) in peanut oils. The interactions between TRA and polyphenolic compounds including kaempferol, taxifolin, dihydrokaempferol and naringenin in pollen grains are investigated by first-principles calculations with M06-2X functional. The adsorption ability of TRA is the strongest on kaempferol in the studied systems. Interaction analysis indicates that there are pi-pi interaction and hydrogen bonds during the adsorption. The structure of the polyphenolic compound determines the adsorption ability. The more planar of the structure and the higher number of hydroxyl group in the polyphenolic compound, the better adsorption of the compound for TRA. Moreover, the investigation of solvent effects illustrates that with the increase in the dielectric constant of the solvent, the stability of the adsorption system improves and the adsorption ability weakens. The results play a significant role in developing new excellent solid-phase extraction sorbents for TRA.
Twins Research Australia: A New Paradigm for Driving Twin Research
TWIN RESEARCH AND HUMAN GENETICS
Authors: Murphy, Kate; Lam, Janine; Cutler, Tessa; Tyler, Jess; Calais-Ferreira, Lucas; Li, Shuai; Little, Callie; Ferreira, Paulo; Craig, Jeffrey M.; Scurrah, Katrina J.; Hopper, John L.
Abstract
Twins Research Australia (TRA) is a community of twins and researchers working on health research to benefit everyone, including twins. TRA leads multidisciplinary research through the application of twin and family study designs, with the aim of sustaining long-term twin research that, both now and in the future, gives back to the community. This article summarizes TRA's recent achievements and future directions, including new methodologies addressing causation, linkage to health, economic and educational administrative datasets and to geospatial data to provide insight into health and disease. We also explain how TRA's knowledge translation and exchange activities are key to communicating the impact of twin studies to twins and the wider community. Building researcher capability, providing registry resources and partnering with all key stakeholders, particularly the participants, are important for how TRA is advancing twin research to improve health outcomes for society. TRA provides researchers with open access to its vibrant volunteer membership of twins, higher order multiples (multiples) and families who are willing to consider participation in research. Established four decades ago, this resource facilitates and supports research across multiple stages and a breadth of health domains.