Rabbit Anti-Human TRA (a.a. 1-202) Polyclonal antibody

Background: Function tricuspid regurgitation (TR) is frequently observed in patients undergoing mitral valve surgery. It is unclear that mitral valve repair (MVr) or mitral valve replacement (MVR) has influence on the likelihood of late TR progression. Methods: This study included 193 patients with degenerative mitral valve disease who underwent either MVr or MVR. Detailed preoperative materials, follow-up information, and echocardiographic data were collected and statistically analyzed. Results: At 6 and 12 months postoperatively, MVR patients were more likely to have New York Heart Association (NYHA) class III or IV symptoms than MVr patients (6 mo: 15.2% vs 5.0%, 12 mo: 13.0% vs 4.0%, both P <0.05). At 24 months, the incidence of Grade 1+ TR was significantly higher in MVR patients than MVr patients (25.0% vs 12.9%, P <0.05). In univariate analysis, age (odds ratio [OR] = 1.036, P = 0.036), MVR (OR = 2.256, P = 0.033), and preoperative TR area (TRA; OR = 1.541, P = 0.047) were significant predictors for TR progression. In multivariate logistics analysis, only MVR was independently risk factor (P = 0.006). Subsequently, patients were divided into tricuspid valve repair (TVr) group and untreated group. In both subgroups, MVR patients were associated with significantly larger TRA (P <0.01). Conclusion: MVR was an independent risk factor for TR progression, whether tricuspid valve was treated or not.

This study addressed the relationship between the plasticity index (PI) and the key parameters of the vacuum consolidation process including the consolidation time (t), the degree of consolidation (U), and the thickness of the treated soft soil layer (H) when improving soft ground by vacuum preloading together with vertical drains. For this purpose, the coupled analysis technique which combines SEEP/W and SIGMA/W modules in Geostudio commercial software is applied for the simulation. Three different foundations corresponding to different soft soils in Dinh Vu- Hai Phong, Duyen Hai - Tra Vinh, Nhon Trach - Dong Nai were considered. The suitability of the predicted numerical models was calibrated using experimental results of laboratory and field tests. The results show that it is possible to link the consolidation time of the foundation and PI by a linear relationship. Higher values of PI results in a longer consolidation time. This relationship is clearer when it comes to the foundation with a higher thickness of the treated soft ground. The results of this study, therefore, help technical workers to quickly give suitable predictions about the process of consolidation when applying the vacuum preloading method in soft soil treatment.