Human TMPRSS3 blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-TMPRSS3 antibody

Target

TMPRSS3

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Gene ID

64699

UniProt ID

P57727

Antigen Description

This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, an LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor-associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2012]

Function

peptidase activity; scavenger receptor activity; serine-type endopeptidase activity; sodium channel regulator activity;

Synonyms

TMPRSS3; transmembrane protease, serine 3; DFNB8, DFNB10; transmembrane protease serine 3; serine protease TADG-12; tumor-associated differentially-expressed gene 12 protein; DFNB8; DFNB10; ECHOS1; TADG12;