Human SAV1 blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-Salvador homolog 1 antibody

Target

Salvador homolog 1

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Gene ID

60485

UniProt ID

Q9H4B6

Antigen Description

WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor. [provided by RefSeq, Aug 2012]

Function

protein binding;

Synonyms

SAV1; salvador homolog 1 (Drosophila); protein salvador homolog 1; salvador; WW45; WWP4; hWW45; 1700040G09Rik; WW domain-containing; 45 kDa WW domain protein; SAV;