Product Overview
Blocking/Immunizing peptide for anti-SRGAP2 antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogous loci on human chromosome 1, resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Dec 2012]
Function
Rac GTPase activator activity; Rac GTPase activator activity; Rac GTPase binding; protein binding; protein homodimerization activity;
Synonyms
SRGAP2; SLIT-ROBO Rho GTPase activating protein 2; FNBP2; SRGAP3; SRGAP2A; ARHGAP34; SLIT-ROBO Rho GTPase-activating protein 2; formin-binding protein 2; rho GTPase-activating protein 34;
Citations
Publication ()
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