Synthetic peptide corresponding to a region derived from internal residues of human SLIT-ROBO Rho GTPase activating protein 2
Conjugate
Unconjugated
Applications
Application Notes
IHC: 1:25-1:100
General Notes
This product (Catalog No. DPABH-20294) is a rabbit-derived polyclonal antibody raised against human SRGAP2. This antibody exhibits cross-reactivity with SRGAP2 from mouse and rat. It has been affinity purified by Protein A. This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. Alternatively spliced transcript variants have been described for this locus. DPABH-20294 is suitable for use in IHC (1:25–1:100) application. DPABH-20294 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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