Human SOS1 peptide

Specificity

Expressed in gingival tissues.

Nature

Synthetic

Tag/Conjugate

Unconjugated

SequenceSimilarities

Contains 1 DH (DBL-homology) domain.Contains 1 N-terminal Ras-GEF domain.Contains 1 PH domain.Contains 1 Ras-GEF domain.

Format

Liquid

Preservative

None

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.

Entrez Gene ID

Antigen Description

This gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4. [provided by RefSeq, Jul 2008]

Function

DNA binding; Ras guanyl-nucleotide exchange factor activity; Ras guanyl-nucleotide exchange factor activity; Rho GTPase activator activity; Rho guanyl-nucleotide exchange factor activity; SH3 domain binding; protein binding; protein heterodimerization act

Synonyms

SOS1; son of sevenless homolog 1 (Drosophila); GF1; HGF; NS4; GGF1; GINGF; son of sevenless homolog 1; SOS-1; guanine nucleotide exchange factor; gingival fibromatosis, hereditary, 1;