Human SMARCB1 peptide

Nature

Synthetic

Tag/Conjugate

Unconjugated

SequenceSimilarities

Belongs to the SNF5 family.

Purity

70 - 90% by HPLC.

Format

Liquid

Preservative

None

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.

Entrez Gene ID

Antigen Description

The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function

contributes_to RNA polymerase II core promoter proximal region sequence-specific DNA binding; contributes_to RNA polymerase II distal enhancer sequence-specific DNA binding; Tat protein binding; contributes_to nucleosomal DNA binding; p53 binding; protein

Synonyms

SMARCB1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1; RDT; INI1; SNF5; Snr1; BAF47; MRD15; RTPS1; Sfh1p; hSNFS; SNF5L1; SWNTS1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; hSNF5; SNF5 homolog; BRG1-associated factor 47; integrase interactor 1 protein; malignant rhabdoid tumor suppressor; SWI/SNF-related matrix-associated protein; sucrose nonfermenting, yeast, homolog-like 1;