Product Overview
Blocking/Immunizing peptide for anti-SMARCB1/SNF5/INI1 antibody
Target
SMARCB1 / SNF5 / INI1
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Function
contributes_to RNA polymerase II core promoter proximal region sequence-specific DNA binding; contributes_to RNA polymerase II distal enhancer sequence-specific DNA binding; Tat protein binding; contributes_to nucleosomal DNA binding; p53 binding; protein
Synonyms
SMARCB1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1; RDT; INI1; SNF5; Snr1; BAF47; MRD15; RTPS1; Sfh1p; hSNFS; SNF5L1; SWNTS1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; hSNF5; SNF5 homolog; BRG1-associated factor 47; integrase interactor 1 protein; malignant rhabdoid tumor suppressor; SWI/SNF-related matrix-associated protein; sucrose nonfermenting, yeast, homolog-like 1;
Citations
Publication ()
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