Specifications
Immunogen
SEMA4G (NP_060363, 24 aa ~ 116 aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Target
Alternative Names
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and shortcytoplasmic domain, (semaphorin) 4G; KIAA1619; FLJ20590; MGC102867; semaphorin-4G; OTTHUMP00000020312; OTTHUMP00000020313; OTTHUMP00000224654; OTTHUMP00000224655; OTTHUMP00000224657
Product Background
Antigen Description
Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes, some (if not all) containing plexin proteins. Multiple transcript variants encoding different isoforms have been found for this gene.Mouse monoclonal antibody raised against a partial recombinant SEMA4G.
Pathway
Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem
Citations
Publication ()
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