The protein encoded by this gene links endocytic vesicles to microtubules. This gene is highly expressed in Reed-Sternberg cells of Hodgkin disease. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Function
metal ion binding; microtubule binding; microtubule plus-end binding; nucleic acid binding; protein binding; protein homodimerization activity; tubulin binding; zinc ion binding;
Synonyms
CLIP1; CAP-GLY domain containing linker protein 1; RSN; CLIP; CYLN1; CLIP170; CLIP-170; CAP-Gly domain-containing linker protein 1; cytoplasmic linker protein 1; cytoplasmic linker protein CLIP-170; cytoplasmic linker protein 170 alpha-2; restin (Reed-Steinberg cell-expressed intermediate filament-associated protein);
Citations
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