The protein encoded by this gene links endocytic vesicles to microtubules. This gene is highly expressed in Reed-Sternberg cells of Hodgkin disease. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Pathway
Cell Cycle; Lissencephaly gene (LIS1) in neuronal migration and development; M Phase; Mitotic Anaphase; Mitotic Metaphase and Anaphase; Mitotic Prometaphase; Regulation of Microtubule Cytoskeleton; Resolution of Sister Chromatid Cohesion
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