Product Overview
Recombinant T. pallidum p15 protein fused at the C- terminus with His tag was expressed in E. coli and purified by proprietary chromatographic technique.
Purity
> 95% pure as determined by SDS- PAGE.
Buffer
70mM Tris-HCl pH 8.0, 50mM NaCl, 50% Glycerol, 1.5 M Urea.
Storage
2-8°C short term, -20°C long term
Introduction
Treponema pallidum is the causative agent of syphilis. It is a gram negative spirochete, a helical to sinusoidal bacterium with outer and cytoplasmic membranes, a thin peptidoglycan layer, and periplasmic flagella.
Antigen Description
The 15 kDa lipoprotein of Treponema pallidum is a major immunogen during natural syphilis infection in humans and experimental infection in other hosts. The humoral and cellular immune responses to this molecule appear late in infection as resistance to reinfection is developing.
Keywords
T. pallidum; Treponema pallidum; T. Pallidum p15; Treponema Pallidum p15
Citations
Publication ()
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