The E.coli derived recombinant protein contains the Trp. Pallidum p15 immunodominant regions. The protein contains beta-galactosidase (114 kDa) fused at the N-terminus.
Target
T. pallidum P15
Nature
Recombinant
Tag/Conjugate
Beta-galactosidase
Alternative Names
T. pallidum P15; Treponema pallidum p15
Purity
> 95 % as determined by SDS-PAGE
Format
Liquid
Buffer
20 mM Tris-HCl pH8, 10 mM B-ME and 8 M urea
Preservative
None
Storage
Store at 4°C. DO NOT FREEZE.
Introduction
Treponema pallidum is a gram-negative spirochaete bacterium and is considered to be metabolically crippled. There are at least four known subspecies: T. pallidum pallidum, T. pallidum pertenue, T. pallidum carateum and T. pallidum endemicum. The helical structure of T. pallidum pallidum allows it to move in a corkscrew motion through viscous mediums such as mucus. Treponema pallidum sub sp. pallidum has one of the smallest bacterial genomes at 1.14 million base pairs (Mb) and has limited metabolic capabilities, reflecting its adaptation through genome reduction to the rich environment of mammalian tissue.
Keywords
T. pallidum; Treponema pallidum; T. pallidum p15; Syphilis
Citations
Publication ()
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